Precision NanoSystems, Inc. (PNI) and Entos Pharmaceuticals (Entos) today announced they have entered into a license and supply agreement whereby PNI will provide its scale-up system, technology transfer and support the GMP manufacturing of Entos’ lead candidate. Entos will use the NanoAssemblr Blaze? instrument for preclinical toxicology studies and transition to the NanoAssemblr Scale-Up system for GMP manufacturing of the drug product for clinical studies. PNI will work closely with the Entos team to provide a complete solution with instrumentation tailored to their needs, expertise and services for formulation scale-up and transition to clinical manufacturing towards phase I study. Financial terms of the agreement were not disclosed.
Entos is a healthcare biotechnology company focused on the development of next generation nucleic acid-based therapies using a proprietary Fusogenix drug delivery system. “We have been using the NanoAssemblr Benchtop instrument in our research and are excited to work with PNI as we progress our lead candidate through late stage preclinical and clinical phases of drug development” said John Lewis, CEO of Entos.
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